Here's a look at Dawnguard, the upcoming expansion to The Elder Scrolls V: Skyrim, which looks like a whole chain of events somewhat similar to the Companions quest line, except focusing on vampires rather than werewolves. Also, horseback combat and giant fucking frost trolls. You know, Game Jam shit!
Vampirism was a total pain in the ass in Oblivion, and I didn't think it was worth the trade off of not being able to travel in daylight without taking damage. And if you wanted to reverse the curse, you had to spend hours upon hours toiling through a quest that you may or may not have enough focus to complete. As that was a throw-in and this is an actual entire mass of downloadable content, I'm hoping it's a little better implemented and runs deeper than just faster regeneration and shit. From the looks of it, transforming into a true beast of the night is an option, which is a step in the right direction.